Overview
Dave welcomes comedian Roseanne Barr, actress Aubrey Plaza, and musical guest Jeff the Brotherhood. Top Ten Ways To Describe the Current Weather. Don't mess with her medical marijuana! Roseanne Barr has a stern warning for President Obama. She once suffered a stroke, so does actress Aubrey Plaza qualify for medical marijuana?
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19 - 1Will Arnett, Lisa Lampanelli, Guided by Voices January 03, 2012 -
19 - 2Brian Williams, WU LYF January 04, 2012
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19 - 3Tina Fey, Jeremy Irvine, Barr Brothers January 05, 2012
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19 - 4Kristen Bell, Dan Naturman, Blind Pilot January 06, 2012
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19 - 5Mark Wahlberg, Heather Morris, Snow Patrol January 09, 2012
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19 - 6Kate Beckinsale, Marv Albert, The Little Willies January 10, 2012
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19 - 7Dolly Parton, Alan Zweibel January 11, 2012
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19 - 8Sen. John McCain, Johnny Winter January 12, 2012
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19 - 9Viggo Mortensen, Dennis Regan, Tony Bennett January 13, 2012
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19 - 10Simon Baker, Elizabeth Banks, Seal January 16, 2012
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19 - 11Ricky Gervais, Jessica Chastain, Kathleen Edwards January 17, 2012
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19 - 12Marg Helgenberger, Michael Fassbender, Ellie Goulding January 18, 2012
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19 - 13Kathy Griffin, Simon Helberg, Joseph Arthur January 19, 2012
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19 - 14Dana Carvey, Jon Fisch, Los Campesinos! January 20, 2012
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19 - 15Jennifer Lopez, Rob Schneider, James McCartney January 30, 2012
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19 - 16Bill Murray, Girls' Generation January 31, 2012
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19 - 17Howard Stern, The Airborne Toxic Event February 01, 2012
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19 - 18Woody Harrelson, Stephen Merchant, Lana Del Rey February 02, 2012
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19 - 19Michelle Williams, Jake Johannsen, Ziggy Marley February 03, 2012
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19 - 20Eli Manning, Sarah Michelle Gellar, Die Antwoord February 06, 2012
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19 - 21Denzel Washington, The Fray February 07, 2012
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19 - 22Ryan Reynolds, Ellie Kemper, Dierks Bentley February 08, 2012
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19 - 23Nicolas Cage, Michelle Dockery, The Kills February 09, 2012
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19 - 24David Spade, Betty Wright February 10, 2012
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19 - 25
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19 - 26
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19 - 27
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19 - 28Joan Rivers, Andrew Lincoln, Jason Mraz February 16, 2012
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19 - 29Kristen Wiig, Mike Birbiglia, Butch Walker and the Black Widows February 17, 2012
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19 - 30Jack Hanna, Jesse Tyler Ferguson February 20, 2012
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19 - 31Alec Baldwin, Eric Hutchinson February 21, 2012
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19 - 32Paul Rudd, John Witherspoon, Heartless Bastards February 22, 2012
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19 - 33Kristin Chenoweth, Joe Scarborough, K'naan featuring Nelly Furtado February 23, 2012
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19 - 34Matthew Broderick, Nick Griffin, We Are Augustines February 24, 2012
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19 - 35Ed Helms, Dan Patrick, Lyle Lovett February 27, 2012
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19 - 36Nathan Lane, Pauley Perrette, Estelle February 28, 2012
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19 - 37
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19 - 38Jon Hamm, Ted Alexandro, White Rabbits March 01, 2012
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19 - 39Will Ferrell, Jon Bernthal March 12, 2012
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19 - 40
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19 - 41Martin Short, The Ting Tings March 14, 2012
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19 - 42Michelle Obama, Esperanza Spalding March 19, 2012
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19 - 43Jennifer Lawrence, Gail Collins, The Shins March 20, 2012
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19 - 44Debra Messing, Josh Hutcherson, Oberhofer March 21, 2012
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19 - 45Rachel Maddow, Timothy Olyphant, Train March 26, 2012
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19 - 46Jason Sudeikis, Lionel Richie, Jason Aldean March 27, 2012
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19 - 47Chris Elliott, Mohamed Nasheed, Justin Townes Earle March 28, 2012
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19 - 48Tracy Morgan, Jim Rome, The Broadway musical 'Once' March 29, 2012
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19 - 49Megan Mullally, Joe Wong, Band of Skulls March 30, 2012
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19 - 50
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19 - 51Kiefer Sutherland, Eugene Levy, The Punch Brothers April 04, 2012
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19 - 52Ricky Gervais, Cobie Smulders, Tennis April 09, 2012
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19 - 53Sean Hayes, Shooter Jennings April 10, 2012
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19 - 54Magic Johnson, Larry Bird, Jim Gaffigan, Kaiser Chiefs April 11, 2012
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19 - 55Billy Crystal, Alabama Shakes April 12, 2012
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19 - 56Julia Louis-Dreyfus, Keith Alberstadt, Bonnie Raitt April 13, 2012
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19 - 57Jason Segel, Zach Wahls, Fun April 23, 2012
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19 - 58Amy Poehler, Wendy Williams, Trampled by Turtles April 24, 2012
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19 - 59Rob Lowe, Gov. Brian Schweitzer, The War on Drugs April 25, 2012
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19 - 60Robin Williams, Andrew Luck April 26, 2012
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19 - 61
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19 - 62Don Rickles, Carrie Underwood April 30, 2012
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19 - 63Seth Meyers, Krysten Ritter, Father John Misty May 01, 2012
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19 - 64Stupid Pet Tricks, Johnny Galecki, Norah Jones May 02, 2012
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19 - 65
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19 - 66Anderson Cooper, Yves Rossy, Electric Guest May 04, 2012
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19 - 67Dr. Phil McGraw, Beth Behrs, Spiritualized May 07, 2012
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19 - 68Jim Parsons, Mika Brzezinski, Macy Gray May 08, 2012
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19 - 69Eva Longoria, Tom Dreesen, Florence and The Machine May 09, 2012
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19 - 70
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19 - 71Jon Cryer, Tommy Johnagin, M. Ward May 11, 2012
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19 - 72Kelly Ripa, Adam Scott, Tenacious D May 14, 2012
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19 - 73Brian Williams, El-P May 15, 2012
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19 - 74Betty White, Moses Maddox, Best Coast May 16, 2012
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19 - 75Conan O'Brien, Regina Spektor, John Mayer May 17, 2012
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19 - 76Sacha Baron Cohen, Julie Chen, Beach House May 18, 2012
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19 - 77
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19 - 78Will Smith, Gossip May 22, 2012
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19 - 79Piedmont Bird Callers, Bill O'Reilly, Pitbull May 23, 2012
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19 - 80Joan Rivers, Dario Franchitti, Silversun Pickups June 04, 2012
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19 - 81Neil Patrick Harris, Noomi Rapace, Alan Jackson June 05, 2012
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19 - 82Jane Fonda, Mayor of London Boris Johnson, Jimmy Cliff June 06, 2012
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19 - 83Bill Murray, The Temper Trap June 07, 2012
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19 - 84Mark Wahlberg, Sebastian Vettel, Black Box Revelation June 11, 2012
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19 - 85Jack Hanna, Patti Smith June 12, 2012
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19 - 86Adam Sandler, Jerry Douglas June 13, 2012
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19 - 87Regis Philbin, Lenny Marcus, Elizabeth Cook June 14, 2012
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19 - 88Denis Leary, Olivia Wilde, The Pierces June 18, 2012
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19 - 89Jeff Daniels, Benjamin Walker, Walk the Moon June 19, 2012
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19 - 90Alec Baldwin, Michael Kiwanuka June 20, 2012
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19 - 91Justin Bieber, Michael Ian Black June 21, 2012
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19 - 92Emma Stone, Jimmie Walker, Diamond Rugs June 25, 2012
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19 - 93LeBron James, Andrew Garfield, Maroon 5 June 26, 2012
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19 - 94Channing Tatum, Scott Pelley, The Gaslight Anthem June 27, 2012
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19 - 95Blake Lively, Drew Brees June 28, 2012
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19 - 96
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19 - 97
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19 - 98Bryan Cranston, R.A. Dickey, Zac Brown Band July 11, 2012
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19 - 99Anne Hathaway, Moody McCarthy, Loudon Wainwright III July 12, 2012
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19 - 100Morgan Freeman, Gallagher, Nas July 16, 2012
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19 - 101Roseanne Barr, Aubrey Plaza, Jeff the Brotherhood July 17, 2012
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19 - 102
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19 - 103Woody Harrelson, Todd Barry, Grafitti6 July 19, 2012
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19 - 104Will Ferrell, Rufus Wainwright July 23, 2012
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19 - 105
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19 - 106Jonah Hill, Dr. Leonard Girardi, Milo Greene July 25, 2012
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19 - 107Joel McHale, Andrew Norelli, Will.I.Am July 26, 2012
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19 - 108Andy Samberg, Ashton Eaton, Glen Hansard August 13, 2012
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19 - 109
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19 - 110Tom Brokaw, Dana Vollmer, Beth Orton August 15, 2012
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19 - 111Tracy Morgan, Erik Kynard, Ben Howard August 16, 2012
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19 - 112Kelsey Grammer, Olivia Munn, Train August 20, 2012
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19 - 113Bill Hader, Mary-Louise Parker, The Walkmen August 21, 2012
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19 - 114Rachel Maddow, Serena Williams, Elle King August 22, 2012
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19 - 115Kathy Griffin, Michael Somerville, Josh Turner August 23, 2012
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19 - 116Jake Gyllenhaal, Sharon Osbourne, Neon Trees August 27, 2012
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19 - 117Amy Adams, Paul Teutul Sr. & Paul Teutul Jr., Hacienda August 28, 2012
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19 - 118Michelle Obama, The Chevin August 29, 2012
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19 - 119Bruce Willis, Brian Regan, The Heavy August 30, 2012
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19 - 120Claire Danes, Dwyane Wade, Bob Mould September 04, 2012
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19 - 121Emma Watson, Julie Chen, Matchbox Twenty September 05, 2012
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19 - 122Howard Stern, Jason Aldean September 06, 2012
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19 - 123Joseph Gordon Levitt, Mindy Kaling, Of Gentlemen and Cowards September 17, 2012
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19 - 124President Barack Obama September 18, 2012
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19 - 125Michael Strahan, Arthur Meyer September 19, 2012
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19 - 126Nathan Lane, Ryan Hunter-Reay, The Killers September 21, 2012
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19 - 127Steve Martin, Gotye September 24, 2012
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19 - 128Stupid Human Tricks, Kaley Cuoco, The Whigs September 25, 2012
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19 - 129David Cameron, Jonny Lee Miller September 26, 2012
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19 - 130Jimmy Fallon, Neil Young, Lupe Fiasco September 27, 2012
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19 - 131Regis Philbin, Tom Dreesen, Dwight Yoakam September 28, 2012
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19 - 132Stephen Colbert, Theresa Caputo, Martha Wash October 01, 2012
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19 - 133Martin Short, Kat Dennings October 02, 2012
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19 - 134Tina Fey, Rick Santorum, LP October 03, 2012
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19 - 135Craig Ferguson, Anna Kendrick, The Raveonettes October 04, 2012
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19 - 136Billy Crystal, The Wallflowers October 05, 2012
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19 - 137Jack Hanna, Max Greenfield October 08, 2012
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19 - 138Kevin James, Chris Elliott, Miguel October 09, 2012
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19 - 139Salma Hayek Pinault, Nick Offerman, KISS October 10, 2012
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19 - 140Lucy Liu; Rob Corddry; Daughter October 11, 2012
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19 - 141John Goodman, Jeff Altman, Jamey Johnson with Alison Krauss October 12, 2012
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19 - 142Tom Hanks; Tony Bennett October 22, 2012
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19 - 143Taylor Swift; Rachel Maddow October 23, 2012
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19 - 144Bill O'Reilly; Nicole Snooki Polizzi; The Lumineers October 24, 2012
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19 - 145Donald Trump; Adam Levine; Carly Rae Jepsen October 25, 2012
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19 - 146Dennis Quaid; Krysten Ritter; Diamond Rings October 26, 2012
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19 - 147Denzel Washington, Paul Banks October 29, 2012
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19 - 148Jim Cantore; Ken Burns; Andrew Bird October 30, 2012
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19 - 149Katie Couric; Rita Ora October 31, 2012
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19 - 150Steven Tyler and Joe Perry; Judy Greer; Aerosmith November 01, 2012
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19 - 151Jason Sudeikis; Michael Che; Ultraĩsta November 02, 2012
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19 - 152Ricky Gervais; Simon Helberg; Ty Segall November 05, 2012
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19 - 153Brian Williams; Ne-Yo November 07, 2012
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19 - 154Robin Williams; Lianne La Havas November 08, 2012
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19 - 155Anderson Cooper; Myq Kaplan; Alberta Cross November 09, 2012
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19 - 156Bradley Cooper; Robert Klein; Soundgarden November 12, 2012
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19 - 157Julianna Margulies; Mumford & Sons November 13, 2012
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19 - 158Alec Baldwin; Dirty Projectors November 14, 2012
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19 - 159Zooey Deschanel; Lisa Lampanelli; Donald Fagen November 15, 2012
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19 - 160Dr. Phil McGraw; Carmen Lynch; Divine Fits November 16, 2012
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19 - 161Jessica Biel; Pete Townshend; Philip Phillips November 19, 2012
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19 - 162Amy Poehler; Josh Hutcherson; Tegan and Sara November 20, 2012
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19 - 163Scarlett Johansson; Willie Nelson; Gary Clark Jr. November 21, 2012
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19 - 164Led Zeppelin; John Krasinski; Paloma Faith December 03, 2012
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19 - 165Matt Damon; Martin Freeman; JD McPherson December 04, 2012
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19 - 166Albert Brooks; Diana Krall December 05, 2012
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19 - 167Bill Murray; Vintage Trouble December 06, 2012
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19 - 168Dustin Hoffman; One Direction December 07, 2012
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19 - 169
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19 - 170Amanda Seyfried; Natalia Makarova; Awolnation December 11, 2012
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19 - 171Billy Crystal; James Balong; Grizzly Bear December 12, 2012
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19 - 172Jamie Foxx; Julie Chen; DIIV December 13, 2012
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19 - 173
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19 - 174Tom Cruise; MNDR December 17, 2012
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19 - 175Paul Rudd; Alicia Keys December 18, 2012
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19 - 176Seth Rogen; John Witherspoon December 19, 2012
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19 - 177Katie Holmes; Jon Bon Jovi December 20, 2012
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19 - 178Naomi Watts; Jay Thomas; Darlene Love December 21, 2012